PDZD3 anticorps (AA 258-285)

N° du produit ABIN1538201

Détail du produit anti-PDZD3 anticorps

Antigène: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Épitope: AA 258-285

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZD3 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the Central region of human PDZD3.

Clone: RB37960

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PDZD3 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur PDZD3

Antigène: PDZD3 (PDZ Domain Containing 3 (PDZD3))

Autre désignation: PDZD3 (PDZD3 Produits)

Synonymes: anticorps RGD1559807, anticorps zgc:194812, anticorps IKEPP, anticorps NHERF4, anticorps PDZK2, anticorps NaPi-Cap2, anticorps Pdzk2, anticorps PDZ domain containing 3, anticorps PDZ domain containing 3b, anticorps Pdzd3, anticorps pdzd3b, anticorps PDZD3

Sujet: Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).

ID gène: 79849

NCBI Accession: NP_001161940, NP_079067

UniProt: Q86UT5