MCM8 anticorps (AA 322-350)

N° du produit ABIN1538307

Détail du produit anti-MCM8 anticorps

Antigène: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Épitope: AA 322-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM8 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MCM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the Central region of human MCM8.

Clone: RB36786

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: MCM8 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur MCM8

Antigène: MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Autre désignation: MCM8 (MCM8 Produits)

Synonymes: anticorps C20orf154, anticorps dJ967N21.5, anticorps 5730432L01Rik, anticorps minichromosome maintenance 8 homologous recombination repair factor, anticorps minichromosome maintenance 8 homologous recombination repair factor L homeolog, anticorps MCM8, anticorps Mcm8, anticorps mcm8.L

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Poids moléculaire: 93697

ID gène: 84515

NCBI Accession: NP_001268449, NP_001268450, NP_001268451, NP_115874, NP_877954

UniProt: Q9UJA3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA