Otopetrin 2 anticorps (AA 336-363)

N° du produit ABIN1538326

Détail du produit anti-Otopetrin 2 anticorps

Antigène: Otopetrin 2 (OTOP2)

Épitope: AA 336-363

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Otopetrin 2 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This OTOP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the Central region of human OTOP2.

Clone: RB37737

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: OTOP2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur Otopetrin 2

Antigène: Otopetrin 2 (OTOP2)

Autre désignation: OTOP2 (OTOP2 Produits)

Synonymes: anticorps OTOP2, anticorps 4732464P15, anticorps otopetrin 2, anticorps OTOP2, anticorps otop2, anticorps Otop2

Sujet: Otopetrins are multi-transmembrane domain proteins that share conserved gene and protein structure and are possibly involved in the formation of otoconia and otoliths. Located in the utricle and saccule of the inner ear, otoconia are complex calcium carbonate biominerals that are required for the normal sensation of gravity and linear acceleration. Vertigo and loss of balance may be attributed to degeneration of displacement of otoconia. The otopetrin family consists of three proteins, OTOP1, OTOP2 and OTOP3. These proteins have 12 putative transmembrane domains that are clustered into three otopetrin domains (OD-I, II and III). OTOP1 was the first described member of the Otopetrin family. Mutations of OTOP1 leads to absence of otoconia or otoliths, though inner ear development is normal. OTOP2 and OTOP3 share significant structural similarity with OTOP1 and may also play a role in the formation of mineralized structures.

Poids moléculaire: 62236

ID gène: 92736

NCBI Accession: NP_835454

UniProt: Q7RTS6