REST anticorps (AA 542-570)

N° du produit ABIN1538486

Détail du produit anti-REST anticorps

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Épitope: AA 542-570

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REST est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This REST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-570 amino acids from the Central region of human REST.

Clone: RB36730

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: REST Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur REST

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Autre désignation: REST (REST Produits)

Synonymes: anticorps NRSF, anticorps XBR, anticorps 2610008J04Rik, anticorps AA407358, anticorps xbr, anticorps nrsf, anticorps rest, anticorps resta, anticorps REST, anticorps RE1 silencing transcription factor, anticorps RE1-silencing transcription factor, anticorps RE1-silencing transcription factor S homeolog, anticorps REST, anticorps Rest, anticorps rest.S, anticorps rest, anticorps LOC615792

Sujet: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Poids moléculaire: 121872

ID gène: 5978

NCBI Accession: NP_001180437, NP_005603

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity