This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This PPFIA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-599 amino acids from the Central region of human PPFIA2.
anticorps 5330438O12, anticorps B230207K17Rik, anticorps E130120L08Rik, anticorps mKIAA4112, anticorps PTPRF interacting protein alpha 2, anticorps protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2, anticorps PPFIA2, anticorps Ppfia2
Sujet
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein is most closely related to PPFIA1, a liprin family member known to interact with the protein phosphatase LAR. The expression of this gene is found to be downregulated by androgens in a prostate cancer cell line.