FANCA anticorps (AA 667-694)

N° du produit ABIN1538566

Détail du produit anti-FANCA anticorps

Antigène: FANCA (Fanconi Anemia Group A Protein (FANCA))

Épitope: AA 667-694

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCA est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FANCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-694 amino acids from the Central region of human FANCA.

Clone: RB23899

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: FANCA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur FANCA

Antigène: FANCA (Fanconi Anemia Group A Protein (FANCA))

Autre désignation: FANCA (FANCA Produits)

Synonymes: anticorps FA, anticorps FA-H, anticorps FA1, anticorps FAA, anticorps FACA, anticorps FAH, anticorps FANCH, anticorps AW208693, anticorps Fanconi anemia complementation group A, anticorps Fanconi anemia, complementation group A, anticorps FANCA, anticorps Fanca

Sujet: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

Poids moléculaire: 162775

ID gène: 2175

NCBI Accession: NP_000126, NP_001018122

UniProt: O15360

Pathways: Réparation de l'ADN