TAB3 anticorps (N-Term)
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- Antigène Voir toutes TAB3 Anticorps
- TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
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Épitope
- AA 1-30, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TAB3 est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This MAP3K7IP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAP3K7IP3.
- Clone
- RB36935
- Isotype
- Ig Fraction
- Top Product
- Discover our top product TAB3 Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- MAP3K7IP3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
- Autre désignation
- MAP3K7IP3 (TAB3 Produits)
- Synonymes
- anticorps MAP3K7IP3, anticorps NAP1, anticorps 4921526G09Rik, anticorps Map3k7ip3, anticorps mKIAA4135, anticorps map3k7ip3, anticorps nap1, anticorps tab3, anticorps tab3-a, anticorps tab3-b, anticorps map3k7ip3l, anticorps si:ch211-232d19.8, anticorps si:dkey-30h22.6, anticorps TGF-beta activated kinase 1 and MAP3K7 binding protein 3, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 3, anticorps TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog, anticorps TAB3, anticorps Tab3, anticorps tab3.S, anticorps tab3
- Sujet
- The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
- Poids moléculaire
- 78653
- ID gène
- 257397
- NCBI Accession
- NP_690000
- UniProt
- Q8N5C8
- Pathways
- Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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