This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This CDC20B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human CDC20B.
The timely destruction of key regulators through ubiquitin-mediated proteolysis ensures the orderly progression of the cell cycle. The APC (anaphase-promoting complex) is a major component of this degradation machinery and its activation is required for the execution of critical events. CDC20B has been implicated as a meiosis specific activator of APC and is required for sporulation in budding yeast.