NR1H4 anticorps (N-Term)
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- Antigène Voir toutes NR1H4 Anticorps
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
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Épitope
- AA 18-46, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR1H4 est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This NR1H4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human NR1H4.
- Clone
- RB39466
- Isotype
- Ig Fraction
- Top Product
- Discover our top product NR1H4 Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- NR1H4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))
- Autre désignation
- NR1H4 (NR1H4 Produits)
- Synonymes
- anticorps zgc:110190, anticorps zgc:92742, anticorps NR1H4, anticorps BAR, anticorps FXR, anticorps HRR-1, anticorps HRR1, anticorps RIP14, anticorps AI957360, anticorps Fxr, anticorps Rxrip14, anticorps nuclear receptor subfamily 1, group H, member 5 S homeolog, anticorps nuclear receptor subfamily 1, group H, member 4, anticorps nuclear receptor subfamily 1 group H member 4, anticorps nr1h5.S, anticorps nr1h4, anticorps NR1H4, anticorps Nr1h4
- Sujet
- NR1H4 is a Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
- Poids moléculaire
- 55914
- ID gène
- 9971
- NCBI Accession
- NP_001193906, NP_001193907, NP_001193908, NP_001193921, NP_001193922, NP_005114
- UniProt
- Q96RI1
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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