GRM7 anticorps (N-Term)

N° du produit ABIN1539213

Détail du produit anti-GRM7 anticorps

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Épitope: AA 240-269, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM7 est non-conjugé

Application: Western Blotting (WB)

Homologie: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GRM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the N-terminal region of human GRM7.

Clone: RB36657

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: GRM7 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur GRM7

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Autre désignation: GRM7 (GRM7 Produits)

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 102251

ID gène: 2917

NCBI Accession: NP_000835, NP_870989

UniProt: Q14831

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour