NR2F6 anticorps (N-Term)
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- Antigène Voir toutes NR2F6 Anticorps
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
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Épitope
- AA 25-53, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR2F6 est non-conjugé
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Application
- Western Blotting (WB)
- Homologie
- M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This NR2F6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-53 amino acids from the N-terminal region of human NR2F6.
- Clone
- RB36666
- Isotype
- Ig Fraction
- Top Product
- Discover our top product NR2F6 Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- NR2F6 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
- Autre désignation
- NR2F6 (NR2F6 Produits)
- Synonymes
- anticorps EAR-2, anticorps EAR2, anticorps ERBAL2, anticorps AV090102, anticorps COUP-TF3, anticorps Erbal2, anticorps COUP(II), anticorps NR2F6, anticorps couptf2, anticorps fc94g11, anticorps wu:fc94g11, anticorps zgc:77259, anticorps ear-2, anticorps ear2, anticorps erbal2, anticorps nr2f6l, anticorps wu:fc72d04, anticorps zgc:77260, anticorps nuclear receptor subfamily 2 group F member 6, anticorps nuclear receptor subfamily 2, group F, member 6, anticorps nuclear receptor subfamily 2, group F, member 6a, anticorps nuclear receptor subfamily 2 group F member 6 L homeolog, anticorps nuclear receptor subfamily 2, group F, member 6b, anticorps NR2F6, anticorps Nr2f6, anticorps nr2f6a, anticorps nr2f6.L, anticorps nr2f6, anticorps nr2f6b
- Sujet
- Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock, is required early in the development of the locus coeruleus (LC).
- Poids moléculaire
- 42979
- ID gène
- 2063
- NCBI Accession
- NP_005225
- UniProt
- P10588
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism
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