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APH1A anticorps (N-Term)
APH1A
Reactivité: Souris
WB
Hôte: Lapin
Polyclonal
RB39321
unconjugated
N° du produit ABIN1539365
Détail du produit anti-APH1A anticorps
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Antigène
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APH1A
(Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
Épitope
Tous les épitopes à travers APH1A Anticorps.
AA 41-70, N-Term
Reactivité
Toutes les réactivités sur APH1A Anticorps
Souris
Hôte
Toutes les hôtes sur APH1A Anticorps
Lapin
Clonalité
Toutes les clonalités sur APH1A Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers APH1A Anticorps
Cet anticorp APH1A est non-conjugé
Application
Tous les applications à travers APH1A Anticorps.
Western Blotting (WB)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This APH1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human APH1A.
Clone
RB39321
Isotype
Ig Fraction
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Alternatives
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Information d'application
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Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
APH1A Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Date de péremption
6 months
Détails sur APH1A
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Antigène
APH1A
(Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
Autre désignation
APH1A (APH1A Produits )
Synonymes
anticorps 6530402N02Rik, anticorps APH-1, anticorps APH-1A, anticorps CGI-78, anticorps RGD1311546, anticorps APH-1a, anticorps aph-1 homolog A, gamma-secretase subunit, anticorps aph-1 homolog A, gamma secretase subunit L homeolog, anticorps aph-1 homolog A, gamma secretase subunit, anticorps anterior pharynx defective 1 homolog A (C. elegans), anticorps aph1 homolog A, gamma secretase subunit, anticorps acylamino-acid-releasing enzyme-like, anticorps APH1A, anticorps aph1a.L, anticorps Aph1a, anticorps LOC100219182
Sujet
APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1, MIM 104311) and nicastrin (APH2, MIM 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (APP, MIM 104760) and Notch (MIM 190198).
Poids moléculaire
28996
ID gène
51107
NCBI Accession
NP_001071096 , NP_001230700 , NP_001230701 , NP_057106
UniProt
Q96BI3
Pathways
Signalisation Notch , Neurotrophin Signaling Pathway
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