PAIP2 anticorps (N-Term)

N° du produit ABIN1539498

Détail du produit anti-PAIP2 anticorps

Antigène: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Épitope: AA 7-34, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAIP2 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, C

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PAIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human PAIP2.

Clone: RB30366

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: PAIP2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur PAIP2

Antigène: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Autre désignation: PAIP2 (PAIP2 Produits)

Synonymes: anticorps PAIP2A, anticorps DKFZp469O1314, anticorps 2310050K10Rik, anticorps AU045972, anticorps paip2, anticorps poly(A) binding protein interacting protein 2, anticorps polyadenylate-binding protein-interacting protein 2, anticorps poly(A) binding protein interacting protein 2B L homeolog, anticorps PAIP2, anticorps Paip2, anticorps paip2b.L

Sujet: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

Poids moléculaire: 14984

ID gène: 51247

NCBI Accession: NP_001028284, NP_057564

UniProt: Q9BPZ3