TOPBP1 anticorps (pSer1159)

N° du produit ABIN1539690

Détail du produit anti-TOPBP1 anticorps

Antigène: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Épitope: pSer1159

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOPBP1 est non-conjugé

Application: Dot Blot (DB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TOPBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1159 of human TOPBP1.

Clone: RB36342

Isotype: Ig Fraction

Information d'application

Indications d'application: DB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Phospho-TOPBP1-S1159 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-TOPBP1-S1159 Antibody at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-TOPBP1 (ABIN1539690)

Liu, Graves, Scott, Li, Lin: "Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization." dans: Molecular and cellular biology, Vol. 33, Issue 23, pp. 4685-700, (2013) (PubMed).

Détails sur TOPBP1

Antigène: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Autre désignation: TOPBP1 (TOPBP1 Produits)

Synonymes: anticorps RGD1562949, anticorps TOPBP1, anticorps cut5, anticorps F2P24.3, anticorps F2P24_3, anticorps meiosis defective 1, anticorps TOP2BP1, anticorps 1110031N14Rik, anticorps 2810429C13Rik, anticorps AI256758, anticorps D430026L04Rik, anticorps mKIAA0259, anticorps TopBP1-A, anticorps TopBP1-B, anticorps Xmus101, anticorps XtopBP, anticorps mus101, anticorps top2bp1, anticorps DNA topoisomerase II binding protein 1, anticorps topoisomerase (DNA) II binding protein 1, anticorps dna topoisomerase ii binding protein 1 (IC), anticorps transcription coactivator, anticorps DNA topoisomerase II binding protein 1 L homeolog, anticorps Topbp1, anticorps topbp1, anticorps TOPBP1, anticorps MEI1, anticorps topbp1.L

Sujet: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

Poids moléculaire: 170679

ID gène: 11073

NCBI Accession: NP_008958

UniProt: Q92547

Pathways: Chromatin Binding