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PDK3 anticorps

PDK3 Reactivité: Humain WB Hôte: Souris Monoclonal 431CT6-1 unconjugated
N° du produit ABIN1539888
  • Antigène Voir toutes PDK3 Anticorps
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Reactivité
    • 31
    • 30
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 50
    • 2
    Souris
    Clonalité
    • 50
    • 2
    Monoclonal
    Conjugué
    • 29
    • 6
    • 5
    • 4
    • 4
    • 4
    Cet anticorp PDK3 est non-conjugé
    Application
    • 45
    • 35
    • 21
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    Immunogène
    Purified His-tagged PDK3 protein(Fragment) was used to produced this monoclonal antibody.
    Clone
    431CT6-1
    Isotype
    IgG2b
    Top Product
    Discover our top product PDK3 Anticorps primaire
  • Indications d'application
    WB: 1:100~800
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    PDK3 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Date de péremption
    6 months
  • Antigène
    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
    Autre désignation
    PDK3 (PDK3 Produits)
    Synonymes
    anticorps pdk3, anticorps PDK3, anticorps 2610001M10Rik, anticorps AI035637, anticorps zgc:158702, anticorps pyruvate dehydrogenase kinase 3, anticorps pyruvate dehydrogenase kinase, isozyme 3a, anticorps pyruvate dehydrogenase kinase, isoenzyme 3, anticorps fragile site, 5-azacytidine type, common, fra(1)(q12), anticorps pyruvate dehydrogenase kinase, isozyme 3b, anticorps PDK3, anticorps Pdk3, anticorps pdk3a, anticorps pdk3, anticorps FRA1J, anticorps pdk3b
    Sujet
    The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    46939
    ID gène
    5165
    NCBI Accession
    NP_001135858, NP_005382
    UniProt
    Q15120
    Pathways
    Signalisation PI3K-Akt, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
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