Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Immunogène
This DISC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 701-728 amino acids from the C-terminal region of human DISC1.
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1,11)(q42.1,q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].