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IgD anticorps (N-Term)

Reactivité: Humain WB Hôte: Souris Monoclonal 607CT8-4-4 unconjugated
N° du produit ABIN1539994
  • Antigène Voir toutes IgD Anticorps
    IgD
    Épitope
    • 15
    • 6
    • 2
    • 2
    • 1
    • 1
    AA 37-64, N-Term
    Reactivité
    • 41
    • 10
    Humain
    Hôte
    • 24
    • 17
    • 9
    Souris
    Clonalité
    • 27
    • 23
    Monoclonal
    Conjugué
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IgD est non-conjugé
    Application
    • 22
    • 21
    • 13
    • 13
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    Immunogène
    This IGHD antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-64 amino acids from the N-terminal region of human IGHD.
    Clone
    607CT8-4-4
    Isotype
    IgM
    Top Product
    Discover our top product IgD Anticorps primaire
  • Indications d'application
    WB: 1:100~800
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    IGHD Antibody (N-term)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Date de péremption
    6 months
  • Antigène
    IgD
    Autre désignation
    IGHD (IgD Produits)
    Synonymes
    anticorps IgD, anticorps Igh-5, anticorps immunoglobulin heavy constant delta, anticorps immunoglobulin delta heavy chain constant region, anticorps Ighd, anticorps Igd, anticorps IGHD
    Classe de substances
    Antibody
    Sujet
    IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.
    Poids moléculaire
    42353
    ID gène
    3495
    UniProt
    P01880
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