IgD anticorps (N-Term)
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- Antigène Voir toutes IgD Anticorps
- IgD
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Épitope
- AA 37-64, N-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IgD est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogène
- This IGHD antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-64 amino acids from the N-terminal region of human IGHD.
- Clone
- 607CT8-4-4
- Isotype
- IgM
- Top Product
- Discover our top product IgD Anticorps primaire
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- Indications d'application
- WB: 1:100~800
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- IGHD Antibody (N-term)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- IgD
- Autre désignation
- IGHD (IgD Produits)
- Synonymes
- anticorps IgD, anticorps Igh-5, anticorps immunoglobulin heavy constant delta, anticorps immunoglobulin delta heavy chain constant region, anticorps Ighd, anticorps Igd, anticorps IGHD
- Classe de substances
- Antibody
- Sujet
- IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.
- Poids moléculaire
- 42353
- ID gène
- 3495
- UniProt
- P01880
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