Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
The antibody detects the 27 kDa p53DINP1-alpha. A lower band (~18 kDa) which represents the p53DINP1-beta was also detected in certain tissue and cells.
Purification
Affinity Chromatography.
Immunogène
Synthetic peptide mapping to the N-terminus of Human p53DINP1.
Western Blot: 0.5-4.0 μg/mL. Immunohistochemistry: 5-10 μg/mL. Human Lung tissue lysate can be used as a Positive Control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
anticorps cb1036, anticorps wu:fb70a09, anticorps wu:fi13h08, anticorps zgc:158431, anticorps TP53INP1, anticorps 2700057G22Rik, anticorps SIP, anticorps SIP18, anticorps SIP27, anticorps Stinp, anticorps Teap, anticorps TP53DINP1, anticorps TP53INP1A, anticorps TP53INP1B, anticorps p53DINP1, anticorps Trp53inp1, anticorps tumor protein p53 inducible nuclear protein 1, anticorps tumor protein p53 inducible nuclear protein 1 S homeolog, anticorps transformation related protein 53 inducible nuclear protein 1, anticorps TP53INP1, anticorps tp53inp1.S, anticorps tp53inp1, anticorps Trp53inp1, anticorps Tp53inp1
Sujet
P53DINP1 (p53-dependent damage-inducible nuclear protein 1) encodes two proteins termed p53DINP1-alpha (27 kDa) and p53DINP1-beta (18 kDa). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1 is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.Synonyms: P53DINP1, SIP, Stress-induced protein, Tumor protein p53-inducible nuclear protein 1, p53-dependent damage-inducible nuclear protein 1, p53-inducible nuclear protein 1