Calcineurin A anticorps (AA 450-500)

N° du produit ABIN1574039

Détail du produit anti-Calcineurin A anticorps

Antigène: Calcineurin A (CAN)

Épitope: AA 450-500

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calcineurin A est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Rabbit Anti-Calcineurin A Polyclonal Antibody detects endogenous levels of calcineurin A protein. Sequence homology predicts that it will also react with rat calcineurin A.

Réactivité croisée (Details): Rabbit Anti-Calcineurin A Polyclonal Antibody detects endogenous levels of calcineurin A protein. Sequence homology predicts that it will also react with rat calcineurin A.

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide (KLH-coupled) within AA 450-500 of human calcineurin A protein

Isotype: IgG

Information d'application

Indications d'application: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA: 0.05-0.2 µg/mL
Western blot: 0.5-1 µg/mL
Other applications: user-optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Détails sur Calcineurin A

Antigène: Calcineurin A (CAN)

Autre désignation: Calcineurin A (CAN Produits)

Synonymes: anticorps Cna, anticorps DDBDRAFT_0185021, anticorps DDBDRAFT_0217855, anticorps DDB_0185021, anticorps DDB_0217855, anticorps PPP3CC, anticorps CAN A1/PP2B, anticorps CG1455, anticorps CNA1, anticorps Can, anticorps Cana1, anticorps CnA, anticorps CnnA21EF, anticorps D14, anticorps DmCanA1-100B, anticorps Dmel\\CG1455, anticorps PP2B, anticorps PP2B 21EF, anticorps PpD14, anticorps canA, anticorps pMY4, anticorps calcineurin A, anticorps Calcineurin A, anticorps CaM-dependent protein phosphatase, catalytic subunit, anticorps protein phosphatase 3 catalytic subunit alpha, anticorps Calcineurin A1, anticorps protein phosphatase 3 catalytic subunit beta, anticorps Cna, anticorps NFIA_077970, anticorps ACLA_011200, anticorps PAS_chr3_0414, anticorps canA, anticorps PPP3CA, anticorps CanA1, anticorps PPP3CB

Sujet: Calcineurin is a heterodimer protein that binds to Ca2+. A Ca2+/calmodulin-regulated protein phosphatase, it is composed of a 19 kD calcineurin B (CnB) and a 61 kD calmodulin-binding catalytic subunit, calcineurin A (CnA). Calcineurin A was first detected in skeletal muscle and brain tissues, but it has since been found in all cell types, from yeast to mammalian. Calcineurin A may be responsible for the calmodulin activation property of calcineurin. There is evidence suggesting that alternative splicing could give rise to different forms of calcineurin A.Rabbit Anti-Calcineurin A Polyclonal Antibody is developed in rabbit hosts using a KLH-coupled synthetic peptide within residues 450-500 of human calcineurin A protein (Swiss Prot: Q08209).