AP2M1 anticorps (N-Term)

N° du produit ABIN1574063

Détail du produit anti-AP2M1 anticorps

Antigène: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AP2M1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Rabbit Anti-AP2M1 Polyclonal Antibody detects endogenous levels of human AP2M1 protein. Sequence homology predicts that it will also react with mouse and rat AP2M1 proteins.

Réactivité croisée (Details): Rabbit Anti-AP2M1 Polyclonal Antibody detects endogenous levels of human AP2M1 protein. Sequence homology predicts that it will also react with mouse and rat AP2M1 proteins.

Purification: Immunoaffinity chromatography

Immunogène: Synthetic peptide (KLH-coupled) from N-terminal of human AP2M1 protein

Isotype: IgG

Information d'application

Indications d'application: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA: 0.05-0.2 µg/mL Western blot: 0.5-1 µg/mL
Other applications: user optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Détails sur AP2M1

Antigène: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Autre désignation: AP2M1 (AP2M1 Produits)

Synonymes: anticorps AP50, anticorps CLAPM1, anticorps mu2, anticorps Ap50, anticorps Clapm1, anticorps cb34, anticorps Ap2m1, anticorps dpy-23, anticorps sb:cb34, anticorps zgc:55711, anticorps zgc:85653, anticorps wu:fa97a10, anticorps ap2m1-a, anticorps ap2m1, anticorps zgc:56643, anticorps AP2M1, anticorps adaptor related protein complex 2 mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, anticorps adaptor-related protein complex 2, mu 1 subunit, a, anticorps adaptor related protein complex 2 mu 1 subunit L homeolog, anticorps adaptor-related protein complex 2, mu 1 subunit, b, anticorps AP-2 complex subunit mu-1, anticorps clathrin coat assembly protein AP50, anticorps clathrin coat assembly protein ap50, anticorps AP2M1, anticorps Ap2m1, anticorps ap2m1a, anticorps ap2m1.L, anticorps ap2m1b, anticorps ap2m1, anticorps cgd8_950, anticorps PY06523, anticorps PVX_118455, anticorps PVX_123590, anticorps CpipJ_CPIJ003697

Sujet: AP2M1 is a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunit family. AP2 is a heterotetramer composed of two large adaptins (either alpha-type subunit AP2A1 or AP2A2 paired with beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1). These component link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.Rabbit Anti-AP2M1 Polyclonal Antibody is developed in rabbit hosts using a synthetic peptide (KLH-coupled) from N-terminal of human AP2M1 protein (Swiss Prot: Q96CW1).

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome