PRKAG2 anticorps (C-Term)

N° du produit ABIN1574210

Détail du produit anti-PRKAG2 anticorps

Antigène: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Épitope: C-Term

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAG2 est non-conjugé

Application: Western Blotting (WB)

Specificité: AMPKgamma2 Antibody, pAb, Rabbit detects human endogenous AMPKgamma2 and does not cross-react with AMPKgamma1 and AMPKgamma3. It is predicted to react with mouse and rat AMPKgamma2 according to sequence homology.

Réactivité croisée (Details): AMPKγ2 Antibody, pAb, Rabbit detects human endogenous AMPKγ2 and does not cross-react with AMPKγ1 and AMPKγ3. It is predicted to react with mouse and rat AMPKγ2 according to sequence homology.

Purification: Immunoaffinity chromatography

Immunogène: KLH-coupled synthetic peptide from C-terminal of human AMPKγ2

Isotype: IgG

Information d'application

Indications d'application: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mL Other Applications: User optimized

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C/-20 °C

Stockage commentaire: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Détails sur PRKAG2

Antigène: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Autre désignation: AMPKgamma2 (PRKAG2 Produits)

Synonymes: anticorps MGC82938, anticorps PRKAG2, anticorps si:ch211-230l11.1, anticorps si:dkey-217f4.2, anticorps AAKG, anticorps AAKG2, anticorps CMH6, anticorps H91620p, anticorps WPWS, anticorps 2410051C13Rik, anticorps AI854673, anticorps protein kinase AMP-activated non-catalytic subunit gamma 2, anticorps protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog, anticorps 5'-AMP-activated protein kinase subunit gamma-2, anticorps protein kinase, AMP-activated, gamma 2 non-catalytic subunit b, anticorps protein kinase, AMP-activated, gamma 2 non-catalytic subunit, anticorps Prkag2, anticorps PRKAG2, anticorps prkag2.L, anticorps LOC504219, anticorps prkag2b, anticorps prkag2

Sujet: AMP-activated protein kinase (AMPK) plays an important role in the regulation of energy homeostasis. It is activated by an elevated AMP/ATP ratio caused by cellular and environmental stress, such as heat shock, hypoxia, and ischemia. AMPK is a heterotrimeric complex composed of a catalytic alpha subunit and regulatory beta and gamma subunits, each of which is encoded by two or three distinct genes (alpha1, alpha2, beta1, beta2, gamma1, gamma2, gamma3). AMPKgamma2 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human AMPKgamma2 (Swiss Prot: Q9UGJ0).

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, Ribonucleoside Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, L'effet Warburg