GLG1 anticorps
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- Antigène Voir toutes GLG1 Anticorps
- GLG1 (Golgi Glycoprotein 1 (GLG1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GLG1 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- ESL-1 antibody
- Specificité
- Recombinant human soluble ESL-1
- Purification
- Protein A purified
- Immunogène
- Recombinant human soluble ESL-1
- Isotype
- IgG
- Top Product
- Discover our top product GLG1 Anticorps primaire
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- Indications d'application
- Western Blot: Use 1-5 μg/mL
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS
- Conseil sur la manipulation
- Centrifuge vial prior to opening.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
- Date de péremption
- 24 months
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- Antigène
- GLG1 (Golgi Glycoprotein 1 (GLG1))
- Autre désignation
- ESL-1 (GLG1 Produits)
- Synonymes
- anticorps AI593353, anticorps AW537898, anticorps CFR, anticorps CFR-1, anticorps ESL-1, anticorps MG-160, anticorps MG160, anticorps Selel, anticorps ESL1, anticorps LTCP-1, anticorps golgi glycoprotein 1, anticorps Golgi apparatus protein 1, anticorps golgi apparatus protein 1, anticorps GLG1, anticorps LOC100175586, anticorps Glg1
- Sujet
- Golgi apparatus protein-1, E-selectin ligand-1, Cysteine-rich fibroblast growth factor receptor,E-Selectin ligand-1/ESL-1 (GLG1, Golgi complex-Localized Glycoprotein 1, CFR1, MG160 and Cysteine-rich FGF receptor) is a 150-160 kDa glycoprotein. The amino acid sequence of MG160, a membrane sialoglycoprotein of the medial cisternae of the rat Golgi apparatus, is more than 90 % identical with CFR, a fibroblast growth factor (FGF) binding protein of chicken membranes, and with ESL-1, a ligand for E-selectin of plasma membranes of myeloid cells, furthermore, MG160, isolated by immunoaffinity chromatography from rat brain membranes, binds to basic FGF. The protein has a large luminal domain composed of an initial Proline-Glutamine-rich segment, encoded by an uninterrupted exonic sequence of several CAG-CAA repeats. Expansion of CAG repeats has been implicated in the etiology of several neurodegenerative diseases. The Proline-Glutamine-rich segment is followed by 16 cysteine-rich repeats that contain five potential Asparagine-linked glycosylation sites, which are conserved in the human, rat, mouse, and chicken. The large extracellular domain of the protein is followed by a single transmembrane domain and a 13-amino-acid cytoplasmic carboxy-terminal tail, which is identical to that in the chicken, rat, and mouse. It is expressed in both Golgi and/or the cell membrane of multiple cell typs, including liver stellate cells, neurons, cardiac myocytes, monocytes and bronchial epithelial cells. In the blood, GLG1/ESL-1 collaborates with PSGL-1 to mediate leukocyte binding to endothelial cell surfaces
- ID gène
- 2734
- NCBI Accession
- NM_001145666, NP_001139138
- UniProt
- Q92896
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