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GLG1 anticorps

GLG1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1589833
  • Antigène Voir toutes GLG1 Anticorps
    GLG1 (Golgi Glycoprotein 1 (GLG1))
    Reactivité
    • 41
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 16
    • 2
    Lapin
    Clonalité
    • 24
    • 17
    Polyclonal
    Conjugué
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GLG1 est non-conjugé
    Application
    • 32
    • 19
    • 14
    • 14
    • 13
    • 11
    • 11
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    ESL-1 antibody
    Specificité
    Recombinant human soluble ESL-1
    Purification
    Protein A purified
    Immunogène
    Recombinant human soluble ESL-1
    Isotype
    IgG
    Top Product
    Discover our top product GLG1 Anticorps primaire
  • Indications d'application
    Western Blot: Use 1-5 μg/mL
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Centrifuge vial prior to opening.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
    Date de péremption
    24 months
  • Antigène
    GLG1 (Golgi Glycoprotein 1 (GLG1))
    Autre désignation
    ESL-1 (GLG1 Produits)
    Synonymes
    anticorps AI593353, anticorps AW537898, anticorps CFR, anticorps CFR-1, anticorps ESL-1, anticorps MG-160, anticorps MG160, anticorps Selel, anticorps ESL1, anticorps LTCP-1, anticorps golgi glycoprotein 1, anticorps Golgi apparatus protein 1, anticorps golgi apparatus protein 1, anticorps GLG1, anticorps LOC100175586, anticorps Glg1
    Sujet
    Golgi apparatus protein-1, E-selectin ligand-1, Cysteine-rich fibroblast growth factor receptor,E-Selectin ligand-1/ESL-1 (GLG1, Golgi complex-Localized Glycoprotein 1, CFR1, MG160 and Cysteine-rich FGF receptor) is a 150-160 kDa glycoprotein. The amino acid sequence of MG160, a membrane sialoglycoprotein of the medial cisternae of the rat Golgi apparatus, is more than 90 % identical with CFR, a fibroblast growth factor (FGF) binding protein of chicken membranes, and with ESL-1, a ligand for E-selectin of plasma membranes of myeloid cells, furthermore, MG160, isolated by immunoaffinity chromatography from rat brain membranes, binds to basic FGF. The protein has a large luminal domain composed of an initial Proline-Glutamine-rich segment, encoded by an uninterrupted exonic sequence of several CAG-CAA repeats. Expansion of CAG repeats has been implicated in the etiology of several neurodegenerative diseases. The Proline-Glutamine-rich segment is followed by 16 cysteine-rich repeats that contain five potential Asparagine-linked glycosylation sites, which are conserved in the human, rat, mouse, and chicken. The large extracellular domain of the protein is followed by a single transmembrane domain and a 13-amino-acid cytoplasmic carboxy-terminal tail, which is identical to that in the chicken, rat, and mouse. It is expressed in both Golgi and/or the cell membrane of multiple cell typs, including liver stellate cells, neurons, cardiac myocytes, monocytes and bronchial epithelial cells. In the blood, GLG1/ESL-1 collaborates with PSGL-1 to mediate leukocyte binding to endothelial cell surfaces
    ID gène
    2734
    NCBI Accession
    NM_001145666, NP_001139138
    UniProt
    Q92896
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