GNB3 anticorps (AA 1-230)
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- Antigène Voir toutes GNB3 Anticorps
- GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
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Épitope
- AA 1-230
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GNB3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- MGEMEQLRQE AEQLKKQIAD ARKACADVTL AELVSGLEVV GRVQMRTRRT LRGHLAKIYA MHWATDSKLL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNM CSIYNLKSRE GNVKVSRELS AHTGYLSCCR FLDDNNIVTS SGDTTCALWD IETGQQKTVF VGHTGDCMSL AVSPDFNLFI SGACDASAKL WDVREGTCRQ TFTGHESDIN
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human GNB3 (NP_002066.1).
- Isotype
- IgG
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
- Autre désignation
- GNB3 (GNB3 Produits)
- Synonymes
- anticorps Gnb-3, anticorps MGC68913, anticorps MGC130764, anticorps gnb3, anticorps zgc:73058, anticorps zgc:77780, anticorps wu:fk54b04, anticorps gnb3l, anticorps zgc:92641, anticorps G protein subunit beta 3, anticorps guanine nucleotide binding protein (G protein), beta 3, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3b, anticorps guanine nucleotide binding protein (G protein), beta polypeptide 3a, anticorps GNB3, anticorps Gnb3, anticorps gnb3.S, anticorps gnb3b, anticorps gnb3a
- Sujet
- Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,GNB3,CSNB1H,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Phospholipase Signaling Pathway,MAPK-JNK Signaling Pathway,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Cardiovascular,Blood,Blood Pressure regulation,GNB3
- Poids moléculaire
- 32 kDa/37 kDa
- ID gène
- 2784
- UniProt
- P16520
- Pathways
- Peptide Hormone Metabolism, Myometrial Relaxation and Contraction
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