E2F2 anticorps

N° du produit ABIN7101516

Détail du produit anti-E2F2 anticorps

Antigène: E2F2 (E2F Transcription Factor 2 (E2F2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp E2F2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human E2F2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur E2F2

Antigène: E2F2 (E2F Transcription Factor 2 (E2F2))

Autre désignation: E2F2 (E2F2 Produits)

Synonymes: anticorps E2F-2, anticorps CG1071, anticorps Dmel\\CG1071, anticorps E2F, anticorps E2F2, anticorps dE2F-2, anticorps dE2F2, anticorps dE2f2, anticorps de2f2, anticorps e2f2, anticorps 9230110J10, anticorps E130207A07, anticorps fb40b03, anticorps wu:fb40b03, anticorps E2F transcription factor 2, anticorps si:ch211-160f23.5, anticorps E2F2, anticorps E2f2, anticorps si:ch211-160f23.5

Sujet: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq, Jul 2008],E2F-2,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,Signal Transduction,Transcription Factors,E2F2

Poids moléculaire: 47 kDa

ID gène: 1870

UniProt: Q14209

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication