Ubiquitin B anticorps

N° du produit ABIN7101530

Détail du produit anti-Ubiquitin B anticorps

Antigène: Ubiquitin B (UBB)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Ubiquitin B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human K48-linkage Specific Ubiquitin

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000, IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Ubiquitin B

Antigène: Ubiquitin B (UBB)

Autre désignation: UBB (UBB Produits)

Synonymes: anticorps AL033289, anticorps Rps27a, anticorps Uba52, anticorps Ubb2, anticorps Ubc, anticorps UBC, anticorps Ubiquitin, anticorps UBB, anticorps Ubi-p63E, anticorps im:6892314, anticorps si:ch211-202a12.3, anticorps ubc, anticorps zUBC, anticorps zgc:172187, anticorps ubiquitin B, anticorps ubiquitin C, anticorps UBB, anticorps Ubb, anticorps UBC, anticorps ubb

Sujet: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],HEL-S-50,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,UBB

ID gène: 7314

UniProt: P0CG47

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagy, EGFR Downregulation, Ubiquitin Proteasome Pathway