PIDD anticorps (AA 1-85)
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- Antigène Voir toutes PIDD Anticorps
- PIDD (P53-Induced Death Domain Protein (PIDD))
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Épitope
- AA 1-85
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PIDD est non-conjugé
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- MAATVEGPEL EAAAAAGDAS EDSDAGSRAL PFLGGNRLSL DLYPGGCQQL LHLCVQQPLQ LLQVEFLRLS THEDPQLLEA TLAQL
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human PIDD (NP_665893.2).
- Isotype
- IgG
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- Indications d'application
- WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:100
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- PIDD (P53-Induced Death Domain Protein (PIDD))
- Autre désignation
- PIDD (PIDD Produits)
- Sujet
- The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.,PIDD1,LRDD,PIDD,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,PIDD
- Poids moléculaire
- 33 kDa/37 kDa/58 kDa/66 kDa/82 kDa/97 kDa/99 kDa
- ID gène
- 55367
- UniProt
- Q9HB75
- Pathways
- Signalisation p53, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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