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MOV10 anticorps (AA 1-310)

MOV10 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1680885
  • Antigène Voir toutes MOV10 Anticorps
    MOV10 (Moloney Leukemia Virus 10 (MOV10))
    Épitope
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    AA 1-310
    Reactivité
    • 26
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 1
    Lapin
    Clonalité
    • 24
    • 2
    Polyclonal
    Conjugué
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp MOV10 est non-conjugé
    Application
    • 23
    • 18
    • 17
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    MPSKFSCRQL REAGQCFESF LVVRGLDMET DRERLRTIYN RDFKISFGTP APGFSSMLYG MKIANLAYVT KTRVRFFRLD RWADVRFPEK RRMKLGSDIS KHHKSLLAKI FYDRAEYLHG KHGVDVEVQG PHEARDGQLL IRLDLNRKEV LTLRLRNGGT QSVTLTHLFP LCRTPQFAFY NEDQELPCPL GPGECYELHV HCKTSFVGYF PATVLWELLG PGESGSEGAG TFYIARFLAA VAHSPLAAQL KPMTPFKRTR ITGNPVVTNR IEEGERPDRA KGYDLELSMA LGTYYPPPRL RQLLPMLLQG
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human MOV10 (NP_066014.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:1000 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    MOV10 (Moloney Leukemia Virus 10 (MOV10))
    Autre désignation
    MOV10 (MOV10 Produits)
    Synonymes
    anticorps C77703, anticorps Mov-10, anticorps Capza1, anticorps fSAP113, anticorps gb110, anticorps Mov10 RISC complex RNA helicase, anticorps Moloney leukemia virus 10, anticorps MOV10, anticorps Mov10
    Sujet
    5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs. Required for microRNA (miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC. Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2. Restricts retrotransposition of long interspersed element-1 (LINE-1 in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7. Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity. May function as a messenger ribonucleoprotein (mRNP clearance factor. Exhibits antiviral activity against dengue virus (DENV.,MOV10,fSAP113,gb110,Epigenetics & Nuclear Signaling,RNA Binding,MOV10
    Poids moléculaire
    6 kDa/101 kDa/113 kDa
    ID gène
    4343
    UniProt
    Q9HCE1
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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