NPLOC4 anticorps (AA 1-270)

N° du produit ABIN1681086

Détail du produit anti-NPLOC4 anticorps

Antigène: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Épitope: AA 1-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPLOC4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: MAESIIIRVQ SPDGVKRITA TKRETAATFL KKVAKEFGFQ NNGFSVYINR NKTGEITASS NKSLNLLKIK HGDLLFLFPS SLAGPSSEME TSVPPGFKVF GAPNVVEDEI DQYLSKQDGK IYRSRDPQLC RHGPLGKCVH CVPLEPFDED YLNHLEPPVK HMSFHAYIRK LTGGADKGKF VALENISCKI KSGCEGHLPW PNGICTKCQP SAITLNRQKY RHVDNIMFEN HTVADRFLDF WRKTGNQHFG YLYGRYTEHK DIPLGIRAEV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NPLOC4 (NP_060391.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NPLOC4

Antigène: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Autre désignation: NPLOC4 (NPLOC4 Produits)

Synonymes: anticorps NPL4, anticorps AK129375, anticorps Npl4, anticorps mKIAA1499, anticorps NPL4 homolog, ubiquitin recognition factor, anticorps NPLOC4, anticorps Nploc4

Sujet: The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I.,NPLOC4,NPL4,NPL4 homolog,Signal Transduction,NPLOC4

Poids moléculaire: 68 kDa/69 kDa

ID gène: 55666

UniProt: Q8TAT6