NUP98 anticorps (AA 621-920)

N° du produit ABIN1681142

Détail du produit anti-NUP98 anticorps

Antigène: NUP98 (Nucleoporin 98kDa (NUP98))

Épitope: AA 621-920

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUP98 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: SKPVDENHQQ DGDEDSLVSH FYTNPIAKPI PQTPESAGNK HSNSNSVDDT IVALNMRAAL RNGLEGSSEE TSFHDESLQD DREEIENNSY HMHPAGIILT KVGYYTIPSM DDLAKITNEK GECIVSDFTI GRKGYGSIYF EGDVNLTNLN LDDIVHIRRK EVVVYLDDNQ KPPVGEGLNR KAEVTLDGVW PTDKTSRCLI KSPDRLADIN YEGRLEAVSR KQGAQFKEYR PETGSWVFKV SHFSKYGLQD SDEEEEEHPS KTSTKKLKTA PLPPASQTTP LQMALNGKPA PPPQVEKKGQ

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 621-920 of human NUP98 (NP_624357.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NUP98

Antigène: NUP98 (Nucleoporin 98kDa (NUP98))

Autre désignation: NUP98 (NUP98 Produits)

Synonymes: anticorps CG10198, anticorps CG10201, anticorps Dmel\\CG10198, anticorps Nup 96, anticorps Nup 98, anticorps Nup-98, anticorps Nup96, anticorps Nup98, anticorps Nup98-Nup96, anticorps Nup98/96, anticorps l(3)95BCd, anticorps nup145, anticorps nup98-96, anticorps GB12688, anticorps NUP98, anticorps 4732457F17, anticorps AI849286, anticorps im:7151238, anticorps zgc:113968, anticorps zgc:63593, anticorps ADIR2, anticorps NUP196, anticorps NUP96, anticorps Nucleoporin 98-96kD, anticorps nuclear pore complex protein Nup98-Nup96, anticorps nucleoporin 98, anticorps nucleoporin 98kDa, anticorps nucleoporin 98 L homeolog, anticorps Nup98-96, anticorps LOC408335, anticorps NUP98, anticorps LOC587580, anticorps Nup98, anticorps nup98, anticorps nup98.L

Sujet: Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.,NUP98,ADIR2,NUP196,NUP96,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,NUP98

Poids moléculaire: 96 kDa/97 kDa/186 kDa/187 kDa/195 kDa/197 kDa

ID gène: 4928

UniProt: P52948

Pathways: Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome