ARNTL anticorps

N° du produit ABIN7101726

Détail du produit anti-ARNTL anticorps

Antigène: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ARNTL est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human BMAL1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ARNTL

Antigène: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Autre désignation: ARNTL (ARNTL Produits)

Synonymes: anticorps BMAL1, anticorps BMAL1c, anticorps JAP3, anticorps MOP3, anticorps PASD3, anticorps TIC, anticorps bHLHe5, anticorps Bmal1, anticorps ARNTL, anticorps xBmal1, anticorps arntl, anticorps Arnt3, anticorps BMAL1b, anticorps bmal1b', anticorps aryl hydrocarbon receptor nuclear translocator like, anticorps aryl hydrocarbon receptor nuclear translocator-like, anticorps aryl hydrocarbon receptor nuclear translocator like S homeolog, anticorps ARNTL, anticorps Arntl, anticorps arntl.S, anticorps arntl

Sujet: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],BMAL1, BMAL1c, JAP3, MOP3, PASD3, TIC, bHLHe5,Blood,Blood_Blood Pressure regulation,Cancer,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Heart,Heart_Cardiac metabolism,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Neuroscience,Transcription Factors,ARNTL

Poids moléculaire: 68 kDa

ID gène: 406

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, L'effet Warburg