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SMC5 anticorps (AA 872-1101)

SMC5 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1682829
  • Antigène Voir toutes SMC5 Anticorps
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Épitope
    • 15
    • 5
    • 3
    • 1
    • 1
    AA 872-1101
    Reactivité
    • 34
    • 18
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 1
    • 1
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SMC5 est non-conjugé
    Application
    • 22
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    LTEERSRASC FTGLNPTIVQ EYTKREEEIE QLTEELKGKK VELDQYRENI SQVKERWLNP LKELVEKINE KFSNFFSSMQ CAGEVDLHTE NEEDYDKYGI RIRVKFRSST QLHELTPHHQ SGGERSVSTM LYLMALQELN RCPFRVVDEI NQGMDPINER RVFEMVVNTA CKENTSQYFF ITPKLLQNLP YSEKMTVLFV YNGPHMLEPN TWNLKAFQRR RRRITFTQPS
     Réactivité croisée
    Humain, Souris, Rat
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 872-1101 of human SMC5 (NP_055925.2).
    Isotype
    IgG
  • Indications d'application
    WB,1:1000 - 1:3000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Autre désignation
    SMC5 (SMC5 Produits)
    Synonymes
    anticorps F1N13.60, anticorps F1N13_60, anticorps structural maintenance of chromosomes 5, anticorps SMC-5, anticorps SMC5L1, anticorps MLZ-453, anticorps Smc5l1, anticorps mKIAA0594, anticorps mSMC5, anticorps structural maintenance of chromosomes 5, anticorps structural maintenance of chromosomes 5 S homeolog, anticorps SMC5, anticorps smc5, anticorps Smc5, anticorps smc5.S
    Sujet
    Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres cell lines and mediates sumoylation of shelterin complex (telosome components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression, the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome.,SMC5,SMC5L1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,SMC5
    Poids moléculaire
    128 kDa
    ID gène
    23137
    UniProt
    Q8IY18
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