STAT4 anticorps (AA 600-700)

N° du produit ABIN1682909

Détail du produit anti-STAT4 anticorps

Antigène: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Épitope: AA 600-700

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: SESHLGGITF TWVDHSESGE VRFHSVEPYN KGRLSALPFA DILRDYKVIM AENIPENPLK YLYPDIPKDK AFGKHYSSQP CEVSRPTERG DKGYVPSVFI P

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human STAT4 (NP_001230764.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur STAT4

Antigène: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Autre désignation: STAT4 (STAT4 Produits)

Synonymes: anticorps SLEB11, anticorps signal transducer and activator of transcription 4, anticorps STAT4, anticorps stat4, anticorps Stat4

Sujet: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.,STAT4,SLEB11,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,STAT4

Poids moléculaire: 85 kDa

ID gène: 6775

UniProt: Q14765

Pathways: Signalistation JAK/STAT