TDP1 anticorps (AA 1-140)
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- Antigène Voir toutes TDP1 Anticorps
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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Épitope
- AA 1-140
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TDP1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE
- Réactivité croisée
- Humain, Rat
- Attributs du produit
- Polyclonal Antibodies
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TDP1 (NP_060789.2).
- Isotype
- IgG
- Top Product
- Discover our top product TDP1 Anticorps primaire
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- Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- Autre désignation
- TDP1 (TDP1 Produits)
- Synonymes
- anticorps 2810481F14Rik, anticorps 4921509N21Rik, anticorps AI838772, anticorps AW493413, anticorps E430034L06Rik, anticorps MLZ-501, anticorps SCAN1, anticorps tdp1, anticorps MGC83708, anticorps TDP1, anticorps F8M21.60, anticorps F8M21_60, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA phosphodiesterase 1, anticorps tyrosyl-DNA Phosphodiesterase (Tdp1), anticorps tyrosyl-DNA phosphodiesterase 1 L homeolog, anticorps tyrosyl-DNA phosphodiesterase-like protein, anticorps TDP1, anticorps Tc00.1047053511191.10, anticorps Tdp1, anticorps tdp1.L, anticorps tdp1, anticorps PTRG_11198, anticorps MCYG_02121, anticorps MGYG_03035
- Sujet
- The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).,TDP1,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,TDP1
- Poids moléculaire
- 41 kDa/68 kDa
- ID gène
- 55775
- UniProt
- Q9NUW8
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