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KAP1 anticorps (AA 576-835)

Name: KAP1 anticorps (AA 576-835)
Brand: antibodies-online
SKU: ABIN1683037
Price: 722.37 EUR
Availability: InStock

TRIM28 Reactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated

Western Blotting (WB) image for anti-Tripartite Motif Containing 28 (TRIM28) (AA 576-835) antibody (ABIN1683037) (KAP1 anticorps (AA 576-835))

Immunohistochemistry of paraffin-embedded human esophageal cancer using K/K/TRIM28 Rabbit pAb at dilution of 1:200 (40x lens). (KAP1 anticorps (AA 576-835))

IHC

Western blot analysis of extracts of various cell lines, using K/K/TRIM28 antibody at 1:1000 dilution. (KAP1 anticorps (AA 576-835))

Immunofluorescence analysis of C6 cells using K/K/TRIM28 Polyclonal Antibody at dilution of 1:100 (40x lens). (KAP1 anticorps (AA 576-835))

Immunofluorescence analysis of L929 cells using K/K/TRIM28 Polyclonal Antibody at dilution of 1:100 (40x lens). (KAP1 anticorps (AA 576-835))

Immunohistochemistry of paraffin-embedded mouse spinal cord using K/K/TRIM28 Rabbit pAb at dilution of 1:200 (40x lens). (KAP1 anticorps (AA 576-835))

IHC

Immunohistochemistry of paraffin-embedded human breast cancer using K/K/TRIM28 Rabbit pAb at dilution of 1:200 (40x lens). (KAP1 anticorps (AA 576-835))

IHC

Immunohistochemistry of paraffin-embedded rat ovary using K/K/TRIM28 Rabbit pAb at dilution of 1:200 (40x lens). (KAP1 anticorps (AA 576-835))

IHC

8 images

(1 reference)

N° du produit ABIN1683037

Fiche de données

Antigène Voir toutes KAP1 (TRIM28) Anticorps

KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))
Épitope
22

15

9

8

6

6

5

5

4

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 576-835
Reactivité
101

45

41

10

8

8

7

5

4

2

1

1

1
Humain
Hôte
102

15

4
Lapin
Anticorps secondaires appropriés
Clonalité
97

24
Polyclonal
Conjugué
61

8

8

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
Cet anticorp KAP1 est non-conjugé
Application
79

37

35

27

26

22

21

21

18

13

6

4

4

3

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence

PVLMALAEGP GAEGPRLASP SGSTSSGLEV VAPEGTSAPG GGPGTLDDSA TICRVCQKPG DLVMCNQCEF CFHLDCHLPA LQDVPGEEWS CSLCHVLPDL KEEDGSLSLD GADSTGVVAK LSPANQRKCE RVLLALFCHE PCRPLHQLAT DSTFSLDQPG GTLDLTLIRA RLQEKLSPPY SSPQEFAQDV GRMFKQFNKL TEDKADVQSI IGLQRFFETR MNEAFGDTKF SAVLVEPPPM SLPGAGLSSQ ELSGGPGDGP

Réactivité croisée

Humain, Souris, Rat

Attributs du produit

Polyclonal Antibodies

Purification

Affinity purification

Immunogène

Recombinant fusion protein containing a sequence corresponding to amino acids 576-835 of human KAP1/KAP1/TRIM28 (NP_005753.1).

Isotype

IgG

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Indications d'application

WB,1:1000 - 1:3000,IHC,1:100 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions

For Research Use only
Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Avoid freeze / thaw cycles.
Han, Cai, Gao, Meng, Gao, Wu, Duan, Wang, Dinislam, Lin, Kang, Jiang: "Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma." dans: Cancer letters, Vol. 419, pp. 280-290, (2019) (PubMed).
Antigène

KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Autre désignation

TRIM28 (TRIM28 Produits)

Sujet

The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.,KAP1,PPP1R157,RNF96,TF1B,TIF1B,TRIM28,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,TRIM28

Poids moléculaire

79 kDa/88 kDa

ID gène

10155

UniProt

Q13263

Pathways

Signalisation Hedgehog, Positive Regulation of Response to DNA Damage Stimulus