AMIGO1 anticorps (AA 554-574)

N° du produit ABIN1686647

Détail du produit anti-AMIGO1 anticorps

Antigène: AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))

Épitope: AA 554-574

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AMIGO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificité: Detects ~60-80 kDa depending on maturity/glycosylation.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 554-574 (cytoplasmic C-terminus) of human AMIGO-1

Clone: S86-36

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN1686647 was sufficient for detection of AMIGO-1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur AMIGO1

Antigène: AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))

Autre désignation: AMIGO1 (AMIGO1 Produits)

Synonymes: anticorps A, anticorps Amigo, anticorps ali2, anticorps AMIGO, anticorps AMIGO-1, anticorps adhesion molecule with Ig like domain 1, anticorps Amigo1, anticorps AMIGO1

Sujet: The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, also designated Alivin2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin3) plays a role in hemophilic and/or heterophilic cell-cell interaction and signal transduction.

ID gène: 57463

NCBI Accession: NP_065754

UniProt: Q86WK6