Complement C4 anticorps (AA 21-120) (AbBy Fluor® 350)
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- Antigène Voir toutes Complement C4 (C4) Anticorps
- Complement C4 (C4) (Complement 4 (C4))
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Épitope
- AA 21-120
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Complement C4 est conjugé à/à la AbBy Fluor® 350
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Complement C4
- Isotype
- IgG
- Top Product
- Discover our top product C4 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Complement C4 (C4) (Complement 4 (C4))
- Autre désignation
- C4a+C4b (C4 Produits)
- Synonymes
- anticorps C4B1, anticorps C4B12, anticorps C4B2, anticorps C4B3, anticorps C4B5, anticorps C4BD, anticorps C4B_2, anticorps C4F, anticorps CH, anticorps CO4, anticorps CPAMD3, anticorps C4, anticorps C4A2, anticorps C4A3, anticorps C4A4, anticorps C4A6, anticorps C4AD, anticorps C4S, anticorps CPAMD2, anticorps RG, anticorps C4-1, anticorps C4b, anticorps C4-2, anticorps Slp, anticorps Ss, anticorps complement C4B (Chido blood group), anticorps complement C4A (Rodgers blood group), anticorps complement component 4A (Rodgers blood group), anticorps complement 4, anticorps complement component 4A, anticorps complement component 4B (Chido blood group), anticorps C4B, anticorps C4A, anticorps C4a, anticorps C4, anticorps C4b
- Sujet
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Synonyms: C4, RG, C4S, CO4, C4A2, C4A3, C4A4, C4A6, C4AD, CPAMD2, CH, C4F, C4B1, C4B2, C4B3, C4B5, C4BD, C4B12, C4B_2, CPAMD3, Complement C4-A, Acidic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A
Background: Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
- ID gène
- 720, 721
- UniProt
- P0C0L4
- Pathways
- Système du Complément
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