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AFAP1L2 anticorps (AbBy Fluor® 350)

AFAP1L2 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal AbBy Fluor® 350
N° du produit ABIN1692927
  • Antigène Voir toutes AFAP1L2 Anticorps
    AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
    Reactivité
    • 20
    • 19
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 21
    • 2
    Lapin
    Clonalité
    • 21
    • 2
    Polyclonal
    Conjugué
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AFAP1L2 est conjugé à/à la AbBy Fluor® 350
    Application
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Souris
    Homologie
    Human,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human AFAP1L2
    Isotype
    IgG
    Top Product
    Discover our top product AFAP1L2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
    Autre désignation
    Afap1l2 (AFAP1L2 Produits)
    Synonymes
    anticorps KIAA1914, anticorps XB130, anticorps AU041783, anticorps C86904, anticorps mKIAA1914, anticorps RGD1310668, anticorps actin filament associated protein 1 like 2, anticorps actin filament associated protein 1-like 2, anticorps AFAP1L2, anticorps Afap1l2
    Sujet

    Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.

    Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.

    Pathways
    EGFR Signaling Pathway
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