AFAP1L2 anticorps (AbBy Fluor® 350)
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- Antigène Voir toutes AFAP1L2 Anticorps
- AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AFAP1L2 est conjugé à/à la AbBy Fluor® 350
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Application
- Western Blotting (WB)
- Réactivité croisée
- Souris
- Homologie
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human AFAP1L2
- Isotype
- IgG
- Top Product
- Discover our top product AFAP1L2 Anticorps primaire
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- Indications d'application
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- AFAP1L2 (Actin Filament Associated Protein 1-Like 2 (AFAP1L2))
- Autre désignation
- Afap1l2 (AFAP1L2 Produits)
- Synonymes
- anticorps KIAA1914, anticorps XB130, anticorps AU041783, anticorps C86904, anticorps mKIAA1914, anticorps RGD1310668, anticorps actin filament associated protein 1 like 2, anticorps actin filament associated protein 1-like 2, anticorps AFAP1L2, anticorps Afap1l2
- Sujet
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Synonyms: KIAA1914, XB130, Actin filament-associated protein 1-like 2, AF1L2_HUMAN, AFAP1-like protein 2, afap1l2.
Background: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.
- Pathways
- EGFR Signaling Pathway
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