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NOSTRIN anticorps (AA 301-400) (AbBy Fluor® 350)

NOSTRIN Reactivité: Humain IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 350
N° du produit ABIN1693103
  • Antigène Voir toutes NOSTRIN Anticorps
    NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))
    Épitope
    • 14
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    Reactivité
    • 39
    • 13
    • 3
    Humain
    Hôte
    • 41
    • 1
    Lapin
    Clonalité
    • 41
    • 1
    Polyclonal
    Conjugué
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOSTRIN est conjugé à/à la AbBy Fluor® 350
    Application
    • 23
    • 22
    • 12
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NOSTRIN
    Isotype
    IgG
    Top Product
    Discover our top product NOSTRIN Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))
    Autre désignation
    Nostrin (NOSTRIN Produits)
    Synonymes
    anticorps NOSTRIN, anticorps MGC171848, anticorps Daip2, anticorps mDaIP2, anticorps DaIP2, anticorps nitric oxide synthase trafficking, anticorps nitric oxide synthase trafficking L homeolog, anticorps nitric oxide synthase trafficker, anticorps NOSTRIN, anticorps nostrin, anticorps nostrin.L, anticorps Nostrin
    Sujet

    Synonyms: BM247, BM247 homolog, DaIP2, eNOS-trafficking inducer, mDaIP2, MGC20702, Nitric oxide synthase traffic inducer, Nitric oxide synthase trafficker, NOSTN_HUMAN, Nostrin, RP23-431D4.2

    Background: NOSTRIN (nitric oxide synthase trafficker isoform 1), also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins. NOSTRIN is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. It consists of an N-terminal Cdc15 domain with an FCH (Fes/CIP homology) region, two coiled coil domains and a C-terminal SH3 domain. NOSTRIN typically exists as a trimer. It functions as an adaptor protein binding to caveolin-1 via an internal domain and NOS3 via its SH3 domain, forming a ternary complex which facilitates caveolar transport of NOS3. The NOS3 protein is responsible for the production of nitric oxide (NO), a potent mediator in various biological processes. The translocation of NOS3 from the plasma membrane to intracellular vesicle-like structures diminishes NO production. NOSTRIN also interacts with Dynamin and N-WASP via its SH3 domain.

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