Supervillin anticorps (AA 51-150) (AbBy Fluor® 350)

N° du produit ABIN1693466

Détail du produit anti-Supervillin anticorps (AbBy Fluor® 350)

Antigène: Supervillin (SVIL)

Épitope: AA 51-150

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Supervillin est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Supervillin

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Supervillin

Antigène: Supervillin (SVIL)

Autre désignation: Supervillin (SVIL Produits)

Synonymes: anticorps sb:cb867, anticorps svil, anticorps wu:fd05a09, anticorps SVIL, anticorps DKFZp468F0819, anticorps AU024053, anticorps B430302E16Rik, anticorps supervillin a, anticorps supervillin, anticorps supervillin, putative, anticorps svila, anticorps SVIL, anticorps LOC5577073, anticorps CpipJ_CPIJ003700, anticorps Smp_148580, anticorps svil, anticorps Svil

Sujet:

Synonyms: Supervillin, Archvillin, p205/p250, SVIL

Background: Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).

ID gène: 6840

UniProt: O95425