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Acetyl-CoA Carboxylase beta anticorps (pSer220) (AbBy Fluor® 488)

ACACB Reactivité: Humain IF (p), IF (cc) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN1694640
  • Antigène Voir toutes Acetyl-CoA Carboxylase beta (ACACB) Anticorps
    Acetyl-CoA Carboxylase beta (ACACB)
    Épitope
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    pSer220
    Reactivité
    • 27
    • 8
    • 1
    Humain
    Hôte
    • 24
    • 3
    • 1
    Lapin
    Clonalité
    • 27
    • 1
    Polyclonal
    Conjugué
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Acetyl-CoA Carboxylase beta est conjugé à/à la AbBy Fluor® 488
    Application
    • 12
    • 12
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase beta around the phosphorylation site of Ser220
    Isotype
    IgG
    Top Product
    Discover our top product ACACB Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Acetyl-CoA Carboxylase beta (ACACB)
    Autre désignation
    Acetyl Coenzyme A Carboxylase beta (ACACB Produits)
    Synonymes
    anticorps F15C21.2, anticorps F15C21_2, anticorps acetyl-CoA carboxylase 2, anticorps ACC2, anticorps ACCB, anticorps HACC275, anticorps Acc2, anticorps AI597064, anticorps AW743042, anticorps Accb, anticorps acetyl-CoA carboxylase 2, anticorps acetyl-CoA carboxylase beta, anticorps acetyl-Coenzyme A carboxylase beta, anticorps ACC2, anticorps ACACB, anticorps Acacb
    Sujet

    Synonyms: Acetyl Coenzyme A Carboxylase beta phospho S220, Acetyl Coenzyme A Carboxylase beta phospho Ser2210 p-Acetyl Coenzyme A Carboxylase beta phospho S220, ACACB_HUMAN

    Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

    UniProt
    O00763
    Pathways
    AMPK Signaling, Ribonucleoside Biosynthetic Process
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