ARID1B anticorps (AA 1501-1600) (AbBy Fluor® 488)
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- Antigène Voir toutes ARID1B Anticorps
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
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Épitope
- AA 1501-1600
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARID1B est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Sheep,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human ARID1B
- Isotype
- IgG
- Top Product
- Discover our top product ARID1B Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ARID1B (AT Rich Interactive Domain 1B (SWI1-Like) (ARID1B))
- Autre désignation
- ARID1B (ARID1B Produits)
- Synonymes
- anticorps fd07d11, anticorps si:dkey-60a16.3, anticorps wu:fd07d11, anticorps 8030481M12, anticorps 9330189K18Rik, anticorps AI836955, anticorps Ardi1b, anticorps B230217J03Rik, anticorps mKIAA1235, anticorps 6A3-5, anticorps Smcf1, anticorps smcf-1, anticorps BAF250B, anticorps BRIGHT, anticorps DAN15, anticorps ELD/OSA1, anticorps MRD12, anticorps OSA2, anticorps P250R, anticorps AT rich interactive domain 1B (SWI1-like), anticorps AT rich interactive domain 1B (SWI-like), anticorps AT-rich interaction domain 1B, anticorps arid1b, anticorps Arid1b, anticorps ARID1B
- Sujet
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Synonyms: OSA2, 6A3-5, DAN15, MRD12, P250R, BRIGHT, BAF250B, ELD/OSA1, AT-rich interactive domain-containing protein 1B, ARID domain-containing protein 1B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, Osa homolog 2, hOsa2, ARID1B, KIAA1235
Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
- ID gène
- 57492
- UniProt
- Q8NFD5
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