HOOK1 anticorps (AA 551-650) (AbBy Fluor® 488)

N° du produit ABIN1695246

Détail du produit anti-HOOK1 anticorps (AbBy Fluor® 488)

Antigène: HOOK1 (Hook Homolog 1 (HOOK1))

Épitope: AA 551-650

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOOK1 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HOOK1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HOOK1

Antigène: HOOK1 (Hook Homolog 1 (HOOK1))

Autre désignation: HOOK1 (HOOK1 Produits)

Synonymes: anticorps si:dkey-183n20.14, anticorps A930033L17Rik, anticorps azh, anticorps HK1, anticorps HOOK1, anticorps hook microtubule tethering protein 1, anticorps hook microtubule-tethering protein 1, anticorps HOOK1, anticorps hook1, anticorps Hook1

Sujet:

Synonyms: A930033L17Rik, Abnormal spermatozoon head shape, azh, h-hook1, hHK1, HK1, HOOK 1, Hook homolog 1 Drosophila, Hook1, HOOK1_HUMAN, MGC10642, OTTHUMP00000010548, OTTMUSP00000008480, Protein Hook homolog 1, RP23-80B16.4.

Background: Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.

ID gène: 51361

Pathways: SARS-CoV-2 Protein Interactome