FERMT2 anticorps (AA 352-420) (AbBy Fluor® 488)

N° du produit ABIN1695257

Détail du produit anti-FERMT2 anticorps (AbBy Fluor® 488)

Antigène: FERMT2 (Fermitin Family Member 2 (FERMT2))

Épitope: AA 352-420

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FERMT2 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Kindlin 2/MIG2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FERMT2

Antigène: FERMT2 (Fermitin Family Member 2 (FERMT2))

Autre désignation: Kindlin 2/MIG2 (FERMT2 Produits)

Synonymes: anticorps AA960555, anticorps Kindlin-2, anticorps Mig2, anticorps Plekhc1, anticorps KIND2, anticorps MIG2, anticorps PLEKHC1, anticorps UNC112, anticorps UNC112B, anticorps mig-2, anticorps fermitin family member 2, anticorps Fermt2, anticorps FERMT2

Sujet:

Synonyms: FLJ34213, FLJ44462, UNC112, FERM2_HUMAN, Fermitin family homolog 2, Fermt2, KIND2, Kindlin-2, MIG-2, MIG2, Mitogen-inducible gene 2 protein, PH domain-containing family C member 1, Pleckstrin homology domain containing family C with FERM domain member 1, Pleckstrin homology domain-containing family C member 1, PLEKHC1, UNC112B.

Background: Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation. Mig-2 expression is transcriptionally elevated in leiomyomas and could be involved in its hormone-mediated growth of leiomyomas of the uterus. Expression of Mig-2 is ubiquitous, and it is found in numerous tumor tissues.

ID gène: 10979

Pathways: Cell-Cell Junction Organization