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GLDC anticorps (AA 51-150) (AbBy Fluor® 488)

GLDC Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal AbBy Fluor® 488
N° du produit ABIN1695510
  • Antigène Voir toutes GLDC Anticorps
    GLDC (Glycine Dehydrogenase (GLDC))
    Épitope
    • 14
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 46
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 47
    Lapin
    Clonalité
    • 47
    Polyclonal
    Conjugué
    • 18
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GLDC est conjugé à/à la AbBy Fluor® 488
    Application
    • 43
    • 19
    • 12
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GLDC
    Isotype
    IgG
    Top Product
    Discover our top product GLDC Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GLDC (Glycine Dehydrogenase (GLDC))
    Autre désignation
    GLDC (GLDC Produits)
    Synonymes
    anticorps PSPTO1276, anticorps Tb07.43M14.350, anticorps DDBDRAFT_0219205, anticorps DDBDRAFT_0231130, anticorps DDB_0219205, anticorps DDB_0231130, anticorps D030049L12Rik, anticorps D19Wsu57e, anticorps GCE, anticorps GCSP, anticorps HYGN1, anticorps fb23b05, anticorps wu:fb23b05, anticorps zgc:66198, anticorps gldc, anticorps glycine dehydrogenase (decarboxylating) GcvP, anticorps glycine dehydrogenase, anticorps glycine cleavage system P-protein, anticorps glycine decarboxylase, anticorps glycine dehydrogenase (decarboxylating), anticorps glycine decarboxylase S homeolog, anticorps gcvP, anticorps Tb927.7.1910, anticorps Gldc, anticorps GLDC, anticorps gldc, anticorps gldc.S
    Sujet

    Synonyms: GCE, GCSP, GCSP_HUMAN, GLDC, Glycine cleavage system P protein, glycine cleavage system protein P, Glycine decarboxylase, glycine decarboxylase P protein, Glycine dehydrogenase decarboxylating mitochondrial, Glycine dehydrogenase [decarboxylating], mitochondrial, Gycine dehydrogenase decarboxylating, HYGN1, MGC138198, MGC138200, NKH.

    Background: The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.

    ID gène
    2731
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