GNL3L anticorps (AA 210-310) (AbBy Fluor® 488)
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- Antigène Voir toutes GNL3L Anticorps
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
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Épitope
- AA 210-310
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GNL3L est conjugé à/à la AbBy Fluor® 488
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris, Rat
- Homologie
- Human,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GNL3L
- Isotype
- IgG
- Top Product
- Discover our top product GNL3L Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
- Autre désignation
- GNL3L (GNL3L Produits)
- Synonymes
- anticorps SI:zK13A21.8, anticorps flj10613, anticorps flj10613l, anticorps si:dkey-13a21.8, anticorps zgc:110536, anticorps BC020354, anticorps guanine nucleotide binding protein-like 3 (nucleolar)-like, anticorps guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog, anticorps G protein nucleolar 3 like, anticorps gnl3l, anticorps gnl3l.S, anticorps GNL3L, anticorps Gnl3l
- Sujet
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Synonyms: GNL3L_HUMAN, FLJ10613, Guanine nucleotide binding protein-like 3 nucleolar-like, novel GTPase, OTTHUMP00000023374.
Background: GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.
- ID gène
- 54552
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