PRICKLE1 anticorps (AA 551-650) (AbBy Fluor® 488)

N° du produit ABIN1695921

Détail du produit anti-PRICKLE1 anticorps (AbBy Fluor® 488)

Antigène: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Épitope: AA 551-650

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRICKLE1 est conjugé à/à la AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Prickle

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PRICKLE1

Antigène: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Autre désignation: Prickle (PRICKLE1 Produits)

Synonymes: anticorps EPM1B, anticorps RILP, anticorps Rilp, anticorps 1110058P22Rik, anticorps AW215793, anticorps Prickle, anticorps mpk1, anticorps XPk, anticorps pk-B, anticorps prickle, anticorps prickle-B, anticorps Prickle-b, anticorps prickle planar cell polarity protein 1, anticorps prickle planar cell polarity protein 1 L homeolog, anticorps prickle planar cell polarity protein 1 S homeolog, anticorps PRICKLE1, anticorps Prickle1, anticorps prickle1.L, anticorps prickle1.S

Sujet:

Synonyms: FLJ31627, FLJ31937, MGC138902, MGC138903, EPM1B, Prickle 1, Prickle homolog 1 Drosophila, Prickle like protein 1, Prickle-like 1, Prickle1, REST-Interacting LIM Domain Protein, REST/NRSF interacting LIM domain protein 1, RILP, PRIC1_HUMAN.

Background: Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

ID gène: 144165

Pathways: Signalisation WNT, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus