SUMF1 anticorps (AA 301-374) (AbBy Fluor® 488)
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- Antigène Voir toutes SUMF1 Anticorps
- SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))
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Épitope
- AA 301-374
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SUMF1 est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SUMF1
- Isotype
- IgG
- Top Product
- Discover our top product SUMF1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SUMF1 (Sulfatase Modifying Factor 1 (SUMF1))
- Autre désignation
- SUMF1 (SUMF1 Produits)
- Synonymes
- anticorps AAPA3037, anticorps FGE, anticorps AA543204, anticorps AI463102, anticorps AI851573, anticorps sulfatase modifying factor 1, anticorps SUMF1, anticorps Sumf1
- Sujet
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Synonyms: MGC150436, AAPA3037, C alpha formylglycine generating enzyme 1, C-alpha-formylglycine-generating enzyme 1, FGE, FGly generating enzyme, MGC131853, Sulfatase modying factor 1 [Precursor], Sulfatase-modying factor 1, SUMF1, SUMF1_HUMAN, UNQ3037.
Background: SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family. Expressed ubiquitously with highest expression in liver, kidney and pancreas, SUMF1 exists as either a monomer, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, thereby playing an important role in sulfatase activity. Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), a heterogeneous disorder characterized by metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay.
- ID gène
- 285362
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