CLEC12A anticorps (AA 61-160) (AbBy Fluor® 555)
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- Antigène Voir toutes CLEC12A Anticorps
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
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Épitope
- AA 61-160
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CLEC12A est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CLEC12A
- Isotype
- IgG
- Top Product
- Discover our top product CLEC12A Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
- Autre désignation
- CLEC12A (CLEC12A Produits)
- Synonymes
- anticorps MGC179455, anticorps CLL-1, anticorps CLL1, anticorps DCAL-2, anticorps MICL, anticorps D230024O04, anticorps KLRL1, anticorps Micl, anticorps C-type lectin domain family 12 member A, anticorps C-type lectin domain family 12, member a, anticorps C-type lectin domain family 12, member A, anticorps CLEC12A, anticorps Clec12a
- Sujet
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Synonyms: C-type lectin domain family 12 member A, C-type lectin-like molecule 1, CL12A_HUMAN, CLEC12A, CLL-1, DCAL-2, Dendritic cell-associated lectin 2, MICL, Myeloid inhibitory C-type lectin-like receptor.
Background: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer.
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