GARNL1 anticorps (AA 631-730) (AbBy Fluor® 555)
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- Antigène Voir toutes GARNL1 (RALGAPA1) Anticorps
- GARNL1 (RALGAPA1) (Ral GTPase Activating Protein, alpha Subunit 1 (Catalytic) (RALGAPA1))
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Épitope
- AA 631-730
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GARNL1 est conjugé à/à la AbBy Fluor® 555
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GARNL1
- Isotype
- IgG
- Top Product
- Discover our top product RALGAPA1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GARNL1 (RALGAPA1) (Ral GTPase Activating Protein, alpha Subunit 1 (Catalytic) (RALGAPA1))
- Autre désignation
- GARNL1 (RALGAPA1 Produits)
- Synonymes
- anticorps GARNL1, anticorps GRIPE, anticorps TULIP1, anticorps Garnl1, anticorps Tulip1, anticorps tulip1, anticorps tulip1.2, anticorps 2310003F20Rik, anticorps 4930400K19Rik, anticorps AI563624, anticorps mKIAA0884, anticorps p240, anticorps Ral GTPase activating protein catalytic alpha subunit 1, anticorps Ral GTPase activating protein, alpha subunit 1 (catalytic), anticorps Ral GTPase activating protein, alpha subunit 1, anticorps RALGAPA1, anticorps Ralgapa1, anticorps ralgapa1
- Sujet
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Synonyms: DKFZp566D133, DKFZp667F074, GAP related interacting partner to E12, GARN L1, GARNL 1, GRIPE, GTPase activating Rap/RanGAP domain like 1, KIAA0884, Tuberin like protein 1, TULIP 1. TULIP1, RGPA1_HUMAN.
Background: GARNL1 is expressed during embryogenesis with E12. During development, GARNL1 expression decreases, persisting at high levels only in neurons of the adult brain. GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap. GARNL1 is imported to the nucleus via dimerization with E12. GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes. This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12. GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades. In adult brain, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue.
- ID gène
- 253959
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