WISP3 anticorps (AA 221-320) (AbBy Fluor® 555)
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- Antigène Voir toutes WISP3 Anticorps
- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
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Épitope
- AA 221-320
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WISP3 est conjugé à/à la AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Sheep,Horse,Rabbit,Monkey
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human WISP3
- Isotype
- IgG
- Top Product
- Discover our top product WISP3 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
- Autre désignation
- WISP3 (WISP3 Produits)
- Synonymes
- anticorps CCN6, anticorps LIBC, anticorps PPAC, anticorps PPD, anticorps ENSMUSG00000062074, anticorps Gm735, anticorps WISP-3, anticorps RGD1564120, anticorps WISP3, anticorps si:dkey-119m7.6, anticorps WNT1 inducible signaling pathway protein 3, anticorps WISP3, anticorps Wisp3, anticorps wisp3
- Sujet
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Synonyms: CCN 6, CCN family member 6, CCN6, CYR61, LIBC, Lost in inflammatory breast cancer tumor suppressor protein, MGC125987, MGC125988, MGC125989, OTTHUMP00000040421, PPAC, PPD, UNQ462/PRO790/PRO956, WISP 3, WISP-3, WISP3, WISP3_HUMAN, WNT 1 inducible signaling pathway protein 3, Wnt 1 signaling pathway protein 3, WNT1 inducible signaling pathway protein 3, WNT1 inducible signaling pathway protein 3 precursor, WNT1-inducible-signaling pathway protein 3.
Background: Wnt-induced secreted protein (WISP)-1, WISP-2 and WISP-3 are members of the CCN family of growth factors, which include connective tissue growth factor (CTGF) and Cyr61. WISP-1, WISP-2 and WISP-3 share significant sequence similarity, including four conserved cysteine-rich domains, and they are believed to function as dimers in their active forms. WISP-1 expression is observed in various tissues including adult heart, kidney and spleen, while WISP-2 expression predominates in skeletal muscle, colon and ovary. Both WISP-1 and WISP-2 are upregulated in cells transformed with the proto-oncogene Wnt-1, and they are also more highly expressed in human colon tumors, suggesting that these proteins may participate in tumor development. WISP-3 is involved in normal post-natal skeletal growth, and it is also implicated in the development of the autosomal recessive skeletal disorder progressive pseudorheumatoid dysplasia, which affects cartilage homeostasis by disrupting the growth of chondrocyte and normal cell columnar organization.
- ID gène
- 8838
- Pathways
- Signalisation WNT, Growth Factor Binding
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